Endotoxin Test
The Bacterial Endotoxins Test (BET) is a test to detect or quantify endotoxins from Gram-negative bacteria. The endotoxin testing, also known as LAL (Limulus Amebocyte Lysate) testing, is an essential part of pharmaceutical microbiology testing. Endotoxins are pyrogen and fever-inducing substances that can be harmful or even fatal if administered to humans above certain concentrations.
In addition to pharmaceutical products and medical devices, water can also contain endotoxins. Therefore, it is crucial to perform endotoxin testing to monitor water systems routinely.
How SIG can help
SIG laboratory provides endotoxin testing for pharmaceutical products and medical devices, including hemodialysis water and WFI (water for injection).
Method of Analysis

SIG Laboratories uses the Gel Clot testing method with the reference method USP 42-NF 37 :2019 <85> and <161>.
Library of Knowledge
SIG Addresses Industrial Water Safety Challenges through ISO-Standardized Microbial Testing at the NgoMik! #17 Collaborative Webinar
Bogor, September 3, 2026 – Bogor, September 3, 2026. As part of its efforts to introduce the latest methods for microbiological water testing to laboratory practitioners in Indonesia, SIG joined Prolabios Mitra Analitika and the Center for Public Health Laboratory (BB...
SIG Holds Audience with BPDP, Pushes for Synergy to Strengthen Competitiveness of Indonesia’s Palm Oil Industry
Jakarta, September 2, 2026 - SIG held an audience with the Plantation Fund Management Agency (Badan Pengelola Dana Perkebunan/BPDP). The meeting served as a momentum for SIG to introduce its laboratory capabilities in supporting the strengthening of the plantation...
Reading Life Through DNA
Discover Environmental Biodiversity Through eDNA SIG now offers Environmental DNA (eDNA) Analysis powered by genomics technology to help identify biological traces present in the environment. “What lives in this environment? Now, SIG can read it through DNA.” Body...
SIG Laboratory
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