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Subchronic Toxicity

Toxicity tests on pesticide products are carried out to test for specific adverse effects or endpoints, for example, mortality, cancer, teratogenicity, irritation, etc., on certain target species. Furthermore, toxicity testing helps determine the effective dosage for practical application of the pesticide. In addition, the results of toxicity tests are generally required as supporting data for registration of pesticide products before trading for safety purposes.

In Indonesia, toxicity testing is one of the technical requirements in the registration of pesticide products. This is regulated in the Regulation of the Minister of Agriculture.  In this regulation, the toxicity test is divided into three based on the duration of the study, namely the acute toxicity test (±24 hours), subchronic (3 months), and chronic (2 years). Also divided into two based on the study target, namely mammalian toxicity (using rodents as animal models) and the environment (soil and aquatic). However, the need for toxicity testing varies depending on the type of pesticide product proposed.

The subchronic toxicity test referred to in the regulation of pesticide requirements above examines adverse effects, such as carcinogenic, teratogenic, and/or mutagenic, of the product’s active ingredients on model animals after repeated exposure for three months.

 

How SIG can help

The SIG laboratory can conduct toxicity tests on pesticide product matrices following the provisions stipulated in the regulations as an accredited toxicity testing agency.

 

Method of Analysis

The toxicity test method refers to the standard method stipulated by the Director-General on behalf of the Minister of Agriculture.

Berita dan Informasi

SIG Laboratory

Graha SIG, Jl Rasamala No. 20, Taman Yasmin, Bogor, Jawa Barat 16113.

Phone. +62 251 7532 348
WhatsApp. +62 82 111 516 516
Email. marketing-sig@saraswanti.com

SIG Jakarta

Jl. Percetakan Negara No. 52 B RT 006 / RW 001, Rawasari, Cempaka Putih, Jakarta Pusat 10570.

Phone. +62 21 2147 9292  

SIG Surabaya

AMG Tower, 12th Floor, Jl. Dukuh Menanggal 1-A, Gayungan, Surabaya, Jawa Timur, 60234.

Phone. +62 31 8253 1288
WhatsApp. +62 818 885 165
Email. marketing@sigsurabaya.com

SIG Semarang

Jl. Kanfer Raya Blok R No. 4 Pedalangan, Kec. Banyumanik, Kota Semarang, Jawa Tengah 50268.

Phone. +62 24 7004 0541
WhatsApp. +62 812 9000 5165
Email. cs.sigsmg@saraswanti.com

SIG Medan

Jl. Bunga Asoka, Ruko Komp. Asoka Raya Residance No. 1, Medan Selayang, Sumatera Utara 20133,

WhatsApp. +62 822 7207 9665
Email. salesmedan.sig@saraswanti.com

SIG Yogyakarta

WhatsApp. +62 896 4856 9422
Email. arifin.sig@saraswanti.com

SIG Makassar

WhatsApp. +62 853 3843 9816
Email. anwar@sigsurabaya.com

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