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- Acute Toxicity
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Rabbit Pyrogen Test
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LC 50 (Artemia)

1.4 – Dioxane

1,4-dioxane is an impurity that may be present in trace amounts in some cosmetics and personal care products. 1,4-dioxane itself is not used as an intentionally added ingredient but can form as a by-product during the manufacturing process of certain ethoxylated ingredients, such as cosmetics containing sodium laureth sulfate or polyethylene glycol which are usually used in cosmetics and personal care products, including cleansing materials (i.e., detergents), foaming agents, emulsifiers, and solvents.

1,4-dioxane is a potential human carcinogen. The compound 1,4-dioxane is a trace contaminant in some cosmetic products. Because of that we need some sophisticated instruments to detect the 1,4-dioxane and give an accurate result.

In Indonesia 1,4-dioxane in cosmetics is regulated at PerBPOM No. 12 of 2019 of 25 mg/kg or 25 mg/L for all cosmetic products.


How SIG can help

SIG Laboratory can perform 1,4 – Dioxane analysis on a wide variety of cosmetics. Our tests also ascertain whether the 1,4-Dioxane are at the appropriate levels, as specified by national and international regulations.


Method of Analysis

GC method is the most likely technique to be used for testing 1,4-dioxane with many detectors such as mass spectrometry and are equipped with a headspace injection system which aims to increase the detection limit of the test method.

Berita dan Informasi

SIG Laboratory

Graha SIG, Jl Rasamala No. 20, Taman Yasmin, Bogor, Jawa Barat 16113.

Phone. +62 251 7532 348
WhatsApp. +62 82 111 516 516
Email. marketing-sig@saraswanti.com

SIG Jakarta

Jl. Percetakan Negara No. 52 B RT 006 / RW 001, Rawasari, Cempaka Putih, Jakarta Pusat 10570.

Phone. +62 21 2147 9292  

SIG Surabaya

AMG Tower, 12th Floor, Jl. Dukuh Menanggal 1-A, Gayungan, Surabaya, Jawa Timur, 60234.

Phone. +62 31 8253 1288
WhatsApp. +62 818 885 165
Email. marketing@sigsurabaya.com

SIG Semarang

Jl. Bina Remaja No. 1A (Ruko A) Banyumanik, Kota Semarang, Jawa Tengah 50264.

Phone. +62 24 7640 3685
WhatsApp. +62 812 9000 5165
Email. cs.sigsmg@saraswanti.com

SIG Medan

Jl. Bunga Asoka, Ruko Komp. Asoka Raya Residance No. 1, Medan Selayang, Sumatera Utara 20133,

WhatsApp. +62 822 7207 9665
Email. salesmedan.sig@saraswanti.com

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