In the world of cosmetics, Tranexamic Acid is becoming increasingly popular as an effective active ingredient for treating hyperpigmentation and evening out skin tone. This compound has been scientifically proven to offer skin-brightening benefits without the high risk of irritation associated with other brightening agents (Maeda & Naganuma, 2017). SIG understands the importance of safe and effective cosmetic ingredients and ensures compliance with regulations from the Indonesian Food and Drug Authority (BPOM). Let’s explore the benefits, mechanism of action, regulations, and applications of Tranexamic Acid in the cosmetics industry.
What is Tranexamic Acid? Tranexamic Acid (TXA) is a synthetic derivative of the amino acid lysine, originally used in the medical field to control bleeding. However, recent studies have shown that Tranexamic Acid also has positive effects in skincare, particularly in reducing excessive melanin production that leads to hyperpigmentation (Zhang et al., 2020).
Benefits of Tranexamic Acid in Cosmetics
- Treats Melasma and Hyperpigmentation
- Tranexamic Acid works by inhibiting the activity of plasmin, an enzyme involved in the inflammatory response and the stimulation of excessive melanin production (Maeda & Naganuma, 2017).
- It is effective in treating melasma, dark spots, and post-inflammatory hyperpigmentation caused by acne.
- A 2021 review found that intradermal injections of Tranexamic Acid at a concentration of 4 mg/ml were effective in treating melasma, with higher patient satisfaction compared to higher concentrations or hydroquinone (Wang et al., 2021).
- Brightens and Evens Out Skin Tone
- Tranexamic Acid helps reduce the appearance of dark spots and promotes a more even, brightened complexion (Zhang et al., 2020).
- Unlike hydroquinone, Tranexamic Acid is gentler on the skin and has minimal side effects related to irritation.
- Reduces Redness and Inflammation
- With its anti-inflammatory properties, Tranexamic Acid can soothe redness caused by UV exposure or allergic reactions.
- A 2022 study evaluated the effectiveness of a 10% Tranexamic Acid topical serum in reducing inflammatory acne. The results showed a significant reduction in inflammatory acne lesions with minimal side effects (Lee et al., 2022).
- Enhances Sunscreen Effectiveness
- Tranexamic Acid helps protect the skin from the harmful effects of UV rays and can be combined with other ingredients like niacinamide or vitamin C for optimal results.
Regulation of Tranexamic Acid in Cosmetics in Indonesia
In Indonesia, the use of active ingredients in cosmetics is regulated by BPOM to ensure product safety and efficacy. According to BPOM Regulation No. 17 of 2022, amending BPOM Regulation No. 23 of 2019 on Technical Requirements for Cosmetic Ingredients, the maximum allowed concentration of Tranexamic Acid in ready-to-use topical cosmetic products is 3.0%.
According to BPOM regulations, cosmetic products containing Tranexamic Acid must:
- Adhere to safe concentration limits for topical use.
- Be formulated with supporting ingredients that do not cause irritation or adverse skin reactions.
- Make claims that are supported by available scientific evidence.
- Meet safety, efficacy, and quality standards as outlined in the latest BPOM regulations.
Application of Tranexamic Acid in the Cosmetics Industry
Tranexamic Acid has been widely used in various cosmetic products, such as:
- Facial serums combining niacinamide and vitamin C for optimal brightening effects.
- Night creams formulated to reduce dark spots caused by UV exposure.
- Toners and essences that help soothe the skin and improve hydration.
- Sunscreen products containing Tranexamic Acid for extra protection against sun-induced hyperpigmentation.
How SIG Can Help
As an SNI ISO/IEC 17025 accredited testing laboratory and a trusted research facility for cosmetic ingredients, SIG plays a vital role in ensuring the safety and efficacy of skincare and cosmetic products. We offer laboratory testing services including:
- Active ingredient content testing for Tranexamic Acid
- Product stability testing
- Dermatological safety & efficacy testing
- Chemical and microbiological contaminant analysis
For more information about cosmetic and skincare testing services at SIG Laboratory, contact us at 082111516516, visit our website at siglaboratory.com, or visit our office at Graha SIG, Jl Rasamala No. 20, Taman Yasmin, Bogor, Jawa Barat 16113.
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